hey everyone, welcome back to my blog!
this week has been a bit hectic because I’ve been traveling for college admit days as well as managing my usual internship schedule so it’s all been a bit much to handle, but luckily I’ve managed to stay on top of all my work.
the most important/productive task i accomplished this week was nearing the halfway completion mark of my proposal for my clinical practical guideline that is going to be the final product of my project. i’ve essentially accumulated all of the data that i’ve been sharing with you guys but delving into more specifics, especially in terms of the recommended dosages of each medication that should be altered as well as the the statistics on the number of patients currently undergoing opioid therapy as well as those experiencing opioid abuse.
but, apart from working on my proposal, i’ve learned some new information that i feel would be extremely important not only for my project, but also to share with you guys. but before i impart that knowledge, it’s important to note that this project is a very recurring and relevant issue right now so there’s always going to be/are currently many new experiments being conducted on opioid therapy, so not all of my information may be up to date by the time I’m able to present my findings of this project, but hopefully it’ll pave a pathway can i continue to embark on in the future.
now onto the new information I’ve uncovered:
-diet plays a modulatory role in chronic pain by helping manage inflammation/oxidative stress which can reduce the pain for these patients
– activities of various natural compounds contained in foods (phenolic compounds in extra-virgin olive oil (EVO)) have comparable effects to drug management therapy
-carbohydrates with low glycaemic index should be consumed every day (three portions), together with fruits and vegetables (five portions), yogurt (125 ml), red wine (125 ml) and EVO
-weekly: legumes and fish (four portions); white meat, eggs and fresh cheese (two portions); red or processed meats (once per week), occasional sweets
-CP subjects may need a specific customised supplementation (vitamin B12, vitamin D, n-3 fatty acids, fibre)
-effectiveness of CC (collaborative care) and MDD (major depressive disorder) with pain medication and duloxetine
-also effectiveness of CC with pain medication and placebo compared with duloxetine alone on depressive and pain symptoms
–Pain medication was administered according to an algorithm that avoids opiate prescriptions
-paracetamol, COX inhibitors, and pregabalin are offered before opiates
– for MDD and pain, patient’s compliance and placebo effects are more important in attaining effect than choice of one of the treatments.
-Active pain management with COX inhibitors and pregabalin serve as alternatives to tramadol or other opiates
so as you can tell, this week’s research articles focused on the impact of opiates for chronic pain on depression and other mental illnesses to see how that would affect the patient as well as to see the interconnection between the two, and although i haven’t gotten much data from this from RDB this week, i hope to find that out next week as well and truly delve into this topic. truth be told, i think the impact of opiates on mental illnesses will be the finishing topic for my research project.
until next time,